Genomics and Bioinformatics Core

Overview of Services

We offer high-quality genomics services such as massively parallel Next Generation sequencing (DNA and RNA), single cell, epigenome, microbiome and spatial biology that are enhanced by the analytical services provided by talented technical and bioinformatics teams. We are dedicated to providing comprehensive and cost-effective services to UB’s scientific community, partner institutes, other SUNY schools, industrial clients and collaborators. 

Services offered:

Next Generation Sequencing:

Whole Genome Sequencing 
ExomeSeq (human and mouse)
RNASeq (ribosomal removal, PolyA, ultralow input)
miRNA-Seq

Single Cell:

scRNASeq (10X Genomics 3'/5' or Illumina Single Cell 3')
scATACSeq (10X Genomics)
scMultiomics (RNA and ATAC)
Fixed nuclei using 10X Genomics FLEX APEX
Immune Profiling 
Multiplexing options available 

Spatial Biology:

10X Genomics XENIUM (Human/Mouse/Custom)
10X Genomics VISIUM (HD, 3' HD, HD XL)
Protein/Antibody Protocols

Microbiome:

Shotgun Metagenomics
16S V1/V2 or V3/V4 AmpliSeq 
Bacterial Variant Calling
Viral Sequencing (Sars-CoV-2, targeted)

Epigenomics:

ChIPSeq
Bulk ATACSeq (Chromatin Accessibility)
MethylSeq (Targeted or Whole Genome)

qPCR and Digital Droplet PCR Services:

Gene Quantification
Quantitative qPCR
Digital Droplet (FAM/HEX, custom designs)

DNA/RNA extractions:

Manual (TriZol, Qiagen)
Automated (Qiasymphony or Revvity)

Bioinformatics:

Single-Cell RNA Analysis
ChIP-Seq Analysis Package
RNA-Seq Analysis Package
miRNA Analysis Package
Custom Project Requests
A La Carte Bioinformatics 

Leadership

Location and hours of operation

Links and Resources

1. Genomics Core website [Next-Gen Sequencing - Business & Entrepreneur Partnerships - University at Buffalo ]

Contacts